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16 channel silicon probes  (NeuroNexus Technologies)


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    Structured Review

    NeuroNexus Technologies 16 channel silicon probes
    (A) Schematic of the experimental pipeline: stereotaxic frame fixation, probe and syringe implantation, placement in a Faraday cage for signal shielding, and real-time multichannel signal acquisition using Open Ephys software. (B) Representative photograph showing the in vivo surgical site setup with stereotaxic micromanipulators positioning the injection capillary needle, recording probe, and ground wire. Design layout of the linear silicon probe array. (C) Anatomical localization of the region of interest (ROI) in the primary somatosensory cortex, barrel field (S1BF), showing histological trace verification alongside stereotaxic brain atlas coordinates.
    16 Channel Silicon Probes, supplied by NeuroNexus Technologies, used in various techniques. Bioz Stars score: 97/100, based on 2516 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/silicon+microelectrode+array/Silicon+Neural+Probe+%2F+Silicon+Microelectrode+Array/bio_rxiv__64898__2026__10__06__756259-48-18-22
    Average 97 stars, based on 2516 article reviews
    16 channel silicon probes - by Bioz Stars, 2026-11
    97/100 stars

    Images

    1) Product Images from "A Reproducible Cortical Model of Focal Epileptiform Activity with a Multi-Biomarker Analysis Pipeline"

    Article Title: A Reproducible Cortical Model of Focal Epileptiform Activity with a Multi-Biomarker Analysis Pipeline

    Journal: bioRxiv

    doi: 10.64898/2026.10.06.756259

    (A) Schematic of the experimental pipeline: stereotaxic frame fixation, probe and syringe implantation, placement in a Faraday cage for signal shielding, and real-time multichannel signal acquisition using Open Ephys software. (B) Representative photograph showing the in vivo surgical site setup with stereotaxic micromanipulators positioning the injection capillary needle, recording probe, and ground wire. Design layout of the linear silicon probe array. (C) Anatomical localization of the region of interest (ROI) in the primary somatosensory cortex, barrel field (S1BF), showing histological trace verification alongside stereotaxic brain atlas coordinates.
    Figure Legend Snippet: (A) Schematic of the experimental pipeline: stereotaxic frame fixation, probe and syringe implantation, placement in a Faraday cage for signal shielding, and real-time multichannel signal acquisition using Open Ephys software. (B) Representative photograph showing the in vivo surgical site setup with stereotaxic micromanipulators positioning the injection capillary needle, recording probe, and ground wire. Design layout of the linear silicon probe array. (C) Anatomical localization of the region of interest (ROI) in the primary somatosensory cortex, barrel field (S1BF), showing histological trace verification alongside stereotaxic brain atlas coordinates.

    Techniques Used: Software, In Vivo, Injection, Silicon

    (A) Representative 10-s electrophysiological traces recorded with 16-channel silicon probes in vehicle, 4-AP (15 mM), and 4-AP (15 mM) + CBZ (1 mM) groups approximately 30 min after microinjection. (B) Baseline-normalized spectrograms (0–650 Hz) from representative animals in the same experimental groups, displayed across the 16 recording sites over the complete 70-min recording period. The first 10 min correspond to baseline, and the vertical dashed line indicates the time of microinjection. Asterisks indicate the approximate time window from which the representative traces shown in panel A were extracted (∼30 min after injection). Warmer colors indicate increases in spectral power relative to baseline, whereas cooler colors indicate decreases.
    Figure Legend Snippet: (A) Representative 10-s electrophysiological traces recorded with 16-channel silicon probes in vehicle, 4-AP (15 mM), and 4-AP (15 mM) + CBZ (1 mM) groups approximately 30 min after microinjection. (B) Baseline-normalized spectrograms (0–650 Hz) from representative animals in the same experimental groups, displayed across the 16 recording sites over the complete 70-min recording period. The first 10 min correspond to baseline, and the vertical dashed line indicates the time of microinjection. Asterisks indicate the approximate time window from which the representative traces shown in panel A were extracted (∼30 min after injection). Warmer colors indicate increases in spectral power relative to baseline, whereas cooler colors indicate decreases.

    Techniques Used: Silicon, Microinjection, Injection

    Related Articles

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    Article Title: Increased reliance on temporal coding when target sound is softer than the background
    Article Snippet: .. At the targeted site, a durotomy was performed before a silicon
    microelectrode array with 16 channels (A4×4-4mm-200-200-1250-H16-21mm, NeuroNexus Technologies, Inc.) was lowered into the brain at an initial insertion depth of 1.3-1.5 mm from the surface of the brain. ..




    Article Title: Increased reliance on temporal coding when target sound is softer than the background
    Article Snippet: .. At the targeted site, a durotomy was performed before a silicon microelectrode array with 16 channels (A4 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\times$$\end{document} × 4-4mm-200-200-1250-H16-21mm, NeuroNexus Technologies, Inc.) was lowered into the brain at an initial insertion depth of 1.3–1.5 mm from the surface of the brain. ..



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    (A) Schematic of the experimental pipeline: stereotaxic frame fixation, probe and syringe implantation, placement in a Faraday cage for signal shielding, and real-time multichannel signal acquisition using Open Ephys software. (B) Representative photograph showing the in vivo surgical site setup with stereotaxic micromanipulators positioning the injection capillary needle, recording probe, and ground wire. Design layout of the linear silicon probe array. (C) Anatomical localization of the region of interest (ROI) in the primary somatosensory cortex, barrel field (S1BF), showing histological trace verification alongside stereotaxic brain atlas coordinates.

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    Article Title: A Reproducible Cortical Model of Focal Epileptiform Activity with a Multi-Biomarker Analysis Pipeline

    doi: 10.64898/2026.10.06.756259

    Figure Lengend Snippet: (A) Schematic of the experimental pipeline: stereotaxic frame fixation, probe and syringe implantation, placement in a Faraday cage for signal shielding, and real-time multichannel signal acquisition using Open Ephys software. (B) Representative photograph showing the in vivo surgical site setup with stereotaxic micromanipulators positioning the injection capillary needle, recording probe, and ground wire. Design layout of the linear silicon probe array. (C) Anatomical localization of the region of interest (ROI) in the primary somatosensory cortex, barrel field (S1BF), showing histological trace verification alongside stereotaxic brain atlas coordinates.

    Article Snippet: Tungsten stereotrodes consisted of two twisted strands of 25 μm tungsten wire (Advent Research Materials, UK), whereas the 16-channel silicon probes (A1x16-5mm-50-177-A16; NeuroNexus) were connected through an Adpt-A16-OM32 adapter and comprised vertically aligned recording sites spaced 50 μm apart along a single shank, spanning a total distance of 750 μm ( ).

    Techniques: Software, In Vivo, Injection, Silicon

    (A) Representative 10-s electrophysiological traces recorded with 16-channel silicon probes in vehicle, 4-AP (15 mM), and 4-AP (15 mM) + CBZ (1 mM) groups approximately 30 min after microinjection. (B) Baseline-normalized spectrograms (0–650 Hz) from representative animals in the same experimental groups, displayed across the 16 recording sites over the complete 70-min recording period. The first 10 min correspond to baseline, and the vertical dashed line indicates the time of microinjection. Asterisks indicate the approximate time window from which the representative traces shown in panel A were extracted (∼30 min after injection). Warmer colors indicate increases in spectral power relative to baseline, whereas cooler colors indicate decreases.

    Journal: bioRxiv

    Article Title: A Reproducible Cortical Model of Focal Epileptiform Activity with a Multi-Biomarker Analysis Pipeline

    doi: 10.64898/2026.10.06.756259

    Figure Lengend Snippet: (A) Representative 10-s electrophysiological traces recorded with 16-channel silicon probes in vehicle, 4-AP (15 mM), and 4-AP (15 mM) + CBZ (1 mM) groups approximately 30 min after microinjection. (B) Baseline-normalized spectrograms (0–650 Hz) from representative animals in the same experimental groups, displayed across the 16 recording sites over the complete 70-min recording period. The first 10 min correspond to baseline, and the vertical dashed line indicates the time of microinjection. Asterisks indicate the approximate time window from which the representative traces shown in panel A were extracted (∼30 min after injection). Warmer colors indicate increases in spectral power relative to baseline, whereas cooler colors indicate decreases.

    Article Snippet: Tungsten stereotrodes consisted of two twisted strands of 25 μm tungsten wire (Advent Research Materials, UK), whereas the 16-channel silicon probes (A1x16-5mm-50-177-A16; NeuroNexus) were connected through an Adpt-A16-OM32 adapter and comprised vertically aligned recording sites spaced 50 μm apart along a single shank, spanning a total distance of 750 μm ( ).

    Techniques: Silicon, Microinjection, Injection